John-Paul Bacik, PhD

Macromolecular Crystallographer
Protein Sciences Consultant

Guidance & Support

I have comprehensive experience across the complete protein crystallography pipeline (gene to structure), encompassing molecular biology, protein purification, crystallization, diffraction data collection and processing. I provide expert support that ensures robust methodologies and the highest-quality structural outcomes.

Analysis & Review

Having determined, built, and refined a wide range of protein crystallographic structures, I provide rigorous structural analysis and review essential for submission to the Protein Data Bank and to peer-reviewed scientific journals. My process ensures confidence in the accuracy, quality and integrity of structural results.

Scientific Writing & Editing

Extensive experience in scientific writing, editing, figure design and peer review, with a strong track record of delivering clear, effective and publishable research communications. This experience ensures that experimental results are accurately presented, meet journal standards, and withstand rigorous scientific review.

About

I am an independent scientist with over 20 years of experience in molecular biology, protein crystallography, structural biology, biochemical assay development and scientific writing. I provide senior-level scientific expertise that enables insightful data interpretation and publication-ready results. In addition to research conducted in academic (Princeton University, Cornell University) and national (Los Alamos, Argonne) laboratories, I have provided scientific and technical support to leading pharmaceutical and biotechnology organizations including Pfizer, AbbVie, Novartis, Merck, Bristol Myers Squibb and Johnson & Johnson, among others.My work in both team-based and lead roles demonstrates my ability to guide and translate complex experimental data into clear, high-impact scientific results and communications with real-world impact. I am the author of 28 peer-reviewed scientific publications, including first-author articles in Nature Communications, Cell Chemical Biology, and The Journal of Biological Chemistry, and have deposited 45 protein structures in the Protein Data Bank.I am currently available for contract, part-time or advisory engagements as an independent scientific consultant, supporting academic and industry clients.Core expertise: Protein crystallography • Structural biology • Experimental design • Data interpretation & analysis • Scientific writing & editing

John-Paul Bacik, PhD